USC-OGP 2-DE database Two-dimensional polyacrylamide gel electrophoresis database

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Searching in 'USC-OGP 2-DE database' for entry matching: Q99961 USC-OGP 2-DE database:  Q99961 Q99961 General information about the entry View entry in simple text format Entry name SH3G1_HUMAN Primary accession number Q99961 integrated into USC-OGP 2-DE database on  January 17, 2017 (release 1) 2D Annotations were last modified on January 17, 2017 (version 1) General Annotations were last modified on  April 5, 2017 (version 2) Name and origin of the protein Description RecName: Full=Endophilin-A2; AltName: Full=EEN fusion partner of MLL; AltName: Full=Endophilin-2; AltName: Full=Extra eleven-nineteen leukemia fusion gene protein; Short=EEN; AltName: Full=SH3 domain protein 2B; AltName: Full=SH3 domain-containing GRB2-like protein 1;. Gene name Name=SH3GL1 Synonyms=CNSA1, SH3D2B Annotated species Homo sapiens (Human) [TaxID: 9606] Taxonomy Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. References [1]   2D GEL CHARACTERIZATION Author 1., Author 2. Submitted (Mar-2011) to Current 2D PAGE maps for identified proteins How to interpret a protein PLATELET_5-6 {PLATELET 5-6} Homo sapiens (Human)   map experimental info   PLATELET_5-6 MAP LOCATIONS: SPOT OGP-0747: pI=5.93; Mw=34217 Cross-references UniProtKB/Swiss-Prot Q99961; SH3G1_HUMAN. 2D PAGE maps for identified proteins How to interpret a protein map You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw. Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly. Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed. External data extracted from UniProtKB/Swiss-Prot Extracted from UniProtKB/Swiss-Prot, release: 0.0 Entry name SH3G1_HUMAN Primary accession number Q99961 Secondary accession number(s) B4DRA1 E7EVZ4 M0QZV5 Q99668 Sequence was last modified on  May 1, 1997 (version 1) Annotations were last modified on  March 15, 2017 (version 173) Name and origin of the protein Description RecName: Full=Endophilin-A2; AltName: Full=EEN fusion partner of MLL; AltName: Full=Endophilin-2; AltName: Full=Extra eleven-nineteen leukemia fusion gene protein; Short=EEN; AltName: Full=SH3 domain protein 2B; AltName: Full=SH3 domain-containing GRB2-like protein 1; Gene name Name=SH3GL1 Synonyms=CNSA1, SH3D2B Encoded on Name=SH3GL1; Synonyms=CNSA1, SH3D2B Keywords Alternative splicing; Cell junction; Cell projection; Chromosomal rearrangement; Coiled coil; Complete proteome; Cytoplasm; Endocytosis; Endosome; Lipid-binding; Membrane; Phosphoprotein; Proto-oncogene; Reference proteome; SH3 domain. Copyright Copyrighted by the UniProt Consortium, see http://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License Cross-references EMBL X99656; CAA67970.1; -; mRNA EMBL U65999; AAB86800.1; -; mRNA EMBL AF190465; AAF04290.1; -; Genomic_DNA EMBL AK299166; BAG61213.1; -; mRNA EMBL AK097616; -; NOT_ANNOTATED_CDS; mRNA EMBL AC007292; -; NOT_ANNOTATED_CDS; Genomic_DNA EMBL AC011498; -; NOT_ANNOTATED_CDS; Genomic_DNA EMBL BC001270; AAH01270.1; -; mRNA CCDS CCDS32874.1; -. [Q99961-1]; . CCDS CCDS56076.1; -. [Q99961-2]; . CCDS CCDS59335.1; -. [Q99961-3]; . RefSeq NP_001186872.1; NM_001199943.1. [Q99961-2]; . RefSeq NP_001186873.1; NM_001199944.1. [Q99961-3]; . RefSeq NP_003016.1; NM_003025.3. [Q99961-1]; . UniGene Hs.490415; -; . UniGene Hs.97616; -; . ProteinModelPortal Q99961; -; . SMR Q99961; -; . BioGrid 112352; 68; . DIP DIP-29452N; -; . IntAct Q99961; 34; . MINT MINT-128645; -; . STRING 9606.ENSP00000269886; -; . iPTMnet Q99961; -; . PhosphoSitePlus Q99961; -; . BioMuta SH3GL1; -; . DMDM 12643797; -; . OGP Q99961; -; . EPD Q99961; -; . MaxQB Q99961; -; . PaxDb Q99961; -; . PeptideAtlas Q99961; -; . PRIDE Q99961; -; . DNASU 6455; -; . Ensembl ENST00000269886; ENSP00000269886; ENSG00000141985. [Q99961-1]; . Ensembl ENST00000417295; ENSP00000404568; ENSG00000141985. [Q99961-2]; . Ensembl ENST00000598564; ENSP00000470792; ENSG00000141985. [Q99961-3]; . GeneID 6455; -; . KEGG hsa:6455; -; . UCSC uc002maj.4; human. [Q99961-1]; . CTD 6455; -; . DisGeNET 6455; -; . GeneCards SH3GL1; -; . HGNC HGNC:10830; SH3GL1; . HPA HPA021485; -; . MalaCards SH3GL1; -; . MIM 601768; gene; . neXtProt NX_Q99961; -; . OpenTargets ENSG00000141985; -; . PharmGKB PA35736; -; . eggNOG KOG1118; Eukaryota; . eggNOG ENOG410XNYB; LUCA; . GeneTree ENSGT00550000074464; -; . HOGENOM HOG000231641; -; . HOVERGEN HBG052866; -; . InParanoid Q99961; -; . KO K11247; -; . OMA DPLQGLC; -; . OrthoDB EOG091G16FW; -; . PhylomeDB Q99961; -; . TreeFam TF313281; -; . Reactome R-HSA-182971; EGFR downregulation; . Reactome R-HSA-6807004; Negative regulation of MET activity; . Reactome R-HSA-8856825; Cargo recognition for clathrin-mediated endocytosis; . Reactome R-HSA-8856828; Clathrin-mediated endocytosis; . Reactome R-HSA-8875360; InlB-mediated entry of Listeria monocytogenes into host cell; . SIGNOR Q99961; -; . ChiTaRS SH3GL1; human; . GeneWiki SH3GL1; -; . GenomeRNAi 6455; -; . PRO PR:Q99961; -; . Proteomes UP000005640; Chromosome 19; . Bgee ENSG00000141985; -; . CleanEx HS_SH3GL1; -; . ExpressionAtlas Q99961; baseline and differential; . Genevisible Q99961; HS; . GO GO:0030054; C:cell junction; IEA:UniProtKB-KW; . GO GO:0042995; C:cell projection; IEA:UniProtKB-KW; . GO GO:0005737; C:cytoplasm; IDA:BHF-UCL; . GO GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell; . GO GO:0002102; C:podosome; IEA:UniProtKB-SubCell; . GO GO:0045202; C:synapse; IEA:GOC; . GO GO:0045296; F:cadherin binding; IDA:BHF-UCL; . GO GO:0042802; F:identical protein binding; IPI:IntAct; . GO GO:0008289; F:lipid binding; IEA:UniProtKB-KW; . GO GO:0007417; P:central nervous system development; TAS:ProtInc; . GO GO:0007165; P:signal transduction; TAS:ProtInc; . GO GO:0016191; P:synaptic vesicle uncoating; IEA:Ensembl; . Gene3D 1.20.1270.60; -; 1; . InterPro IPR027267; AH/BAR-dom; . InterPro IPR004148; BAR_dom; . InterPro IPR001452; SH3_domain; . Pfam PF03114; BAR; 1; . Pfam PF00018; SH3_1; 1; . PRINTS PR00452; SH3DOMAIN; . SMART SM00721; BAR; 1; . SMART SM00326; SH3; 1; . SUPFAM SSF50044; SSF50044; 1; . PROSITE PS51021; BAR; 1; . PROSITE PS50002; SH3; 1; .

Gateways to other related servers

• The World-2DPAGE Constellation - Entry point to the world-wide 2-DPAGE resources.
• World-2DPAGE Repository - A public repository for gel-based proteomics data linked to protein identification published in the literature.
• World-2DPAGE Portal - A dynamic portal to query simultaneously world-wide gel-based proteomics databases.
• SWISS-2DPAGE - The Geneva Two-dimensional polyacrylamide gel electrophoresis database.
• ExPASy - The resources web server of the Swiss Institute of Bioinformatics

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